HPC Module: BWA
Synopsis
Adds BWA software to your environment
| About This Software | |
|---|---|
| Official Site | http://bio-bwa.sourceforge.net |
| Tags |
Installed Versions
| Version | Install Date | Default? |
|---|---|---|
| 0.7.15 | 2016-06-13 |
Description
BWA is a software package for mapping low-divergent sequences against a large reference genome, such as the human genome. It consists of three algorithms: BWA-backtrack, BWA-SW and BWA-MEM. The first algorithm is designed for Illumina sequence reads up to 100bp, while the rest two for longer sequences ranged from 70bp to 1Mbp. BWA-MEM and BWA-SW share similar features such as long-read support and split alignment, but BWA-MEM, which is the latest, is generally recommended for high-quality queries as it is faster and more accurate. BWA-MEM also has better performance than BWA-backtrack for 70-100bp Illumina reads.
Citation(s)
The short read alignment component (bwa-short) has been published:
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Li H. and Durbin R. (2009) Fast and accurate short read alignment with Burrows-Wheeler Transform. Bioinformatics, 25:1754-60. [PMID: 19451168] If you use BWA-SW, please cite:
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Li H. and Durbin R. (2010) Fast and accurate long-read alignment with Burrows-Wheeler Transform. Bioinformatics, Epub. [PMID: 20080505]
Category
| Library | Programming | Software | SysAdmin |
|---|---|---|---|